Analysis of Arpc1b Gene Expression in Pterygium


Özet Görüntüleme: 184 / PDF İndirme: 91

Yazarlar

DOI:

https://doi.org/10.5281/zenodo.10638197

Anahtar Kelimeler:

ARPC1B, Pterygium, qRT-PCR

Özet

 

Aktin İlişkili Protein 2/3 Kompleks Alt Birim 1B, ARPC1B geninin adıdır. İnsan Arp2 / 3 protein kompleksinin yedi alt birimi vardır ve bu gen bunlardan birini kodlar. Duyusal rodopsin-2 proteini, SOP2 ailesine ait bir bileşendir.

Bu araştırmanın amacı, ARPC1B geninin pterjiyum hastalığını nasıl etkilediğini görmektir hastaların onayı ile ameliyat sırasında doku çıkarıldı. Real-Time PCR ile değerlendirilen bir grup doku seviyesinden cDNA sentezlenecek ARPC1B geninin teknik ekspresyonunu kullanıldı ve pterjiyum tanısı doğrulandı (polimeraz zincir reaksiyonu).

qRT-PCR bulgularına göre pterjium ve normal konjonktival dokularda ARPC1B gen ekspresyon düzeylerinde anlamlı farklılık olmadıgı tespıt edıldı (p>0.005).

 

 

Anahtar Kelimeler: ARPC1B, Pterygium ,qRT-PCR

 

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Yayınlanmış

2024-03-12

Nasıl Atıf Yapılır

AHMED, M., BOZKURT, N., ŞAHİN, K., ŞAVKIN, S., TIĞLI, H., DEMİR, H. D., GÜNEŞ, A., & ATEŞ, H. Ömer. (2024). Analysis of Arpc1b Gene Expression in Pterygium . MAS Uygulamalı Bilimler Dergisi, 9(1), 75–89. https://doi.org/10.5281/zenodo.10638197

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