Tumor Necrosis Factor-α, Interleukin-1 Levels and Thiol/Disulfide Homeostasis in Cattle with Hydatid Cyst
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https://doi.org/10.5281/zenodo.13922784Keywords:
Cattle, hydatid cyst, interleukin-1, thiol/disulfide homeostasisAbstract
Our aim was to determine thiol/disulfide homeostasis and cytokine levels in cattle with hydatid cysts. A total of 30 cattle, 15 infected with hydatid cysts and 15 healthy, were used in the study. Tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1), total thiol, native thiol analyses were performed in serum samples. It was determined that TNF-α and IL-1 levels were significantly increased in cattle infected with hydatid cysts. In cattle infected with hydatid cysts, total thiol and native thiol levels were significantly decreased among biochemical parameters, while disulfide, disulfide/native thiol and disulfide/total thiol and native thiol/total thiol levels were statistically insignificant. In conclusion, the findings obtained from the study suggest that the use of thiol/disulfide homeostasis markers in cattle infected with hydatid cysts will contribute to the pathogenesis of the disease.
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