The Effects of Long-Term Exposure To Textile Dyes On Serum Cytokine And Antioxidant Enzyme Activities

Abstract

The dyehouse works can be used in almost all areas of the industry. Nowadays, the paints used in industry are very diverse with their different chemical properties and different application methods. Oxidative stress and cytokine levels were measured to determine the occupational exposure status of 40 workers in dyehouses of textile industry and 40 employees working in other office work. The oxidant/antioxidant parameters superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx) were found to be statistically significantly lower in the dye-exposed group compared to the control group (p<0.05). The parameters of inflammation biomarkers tumor necrosis factor-? (TNF-?), interleukin-6 (IL-6) and interleukin 1 beta (IL-1ß) were statistically significant higher in the dye-exposed group, compared to the control group (p<0.05). As a result, it is understood that the oxidant-antioxidant and anti-inflammatory cytokine balance status of workers in the dyehouse of a large-scale factory will deteriorate over time.