Open Access

The Biotechnological Potential and Treatment Processes of Cheese Whey

Kafkas University, Faculty of Engineering and Architecture, Department of Civil Engineering, Kars

Abstract

The global rise in dairy product consumption has significantly increased the volume of waste generated by the dairy industry, particularly cheese whey (CW), a by-product rich in organic matter and bioactive compounds. Owing to its high chemical and biological oxygen demand, the untreated discharge of CW poses serious environmental threats. However, its rich composition, which includes proteins, lactose, and minerals, makes whey a promising raw material for environmental management as well as for the production of value-added products. This review offers a comprehensive evaluation of the biotechnological potential of whey and the treatment technologies applied since 2004. Emphasis is placed on anaerobic processes and membrane-based separation techniques, and novel integrated approaches aimed at promoting circular economy principles. The study highlights recent advances in resource recovery, biogas generation, and bioactive compound isolation, while addressing the ecological and economic implications of whey valorization through sustainable and innovative methods.

Keywords

How to Cite

ÇELİKTEN, H. (2025). The Biotechnological Potential and Treatment Processes of Cheese Whey. MAS Journal of Applied Sciences, 10(3), 446–455. https://doi.org/10.5281/zenodo.16731871

References

📄 Antonopoulou, G., Stamatelatou, K., Venetsaneas, N., Kornaros, M., Lyberatos, G., 2008. Biohydrogen and methane production from cheese whey in a two-stage anaerobic process. Industrial & Engineering Chemistry Research, 47(15): 5227-5233.
📄 Antonopoulou, G., Ntaikou, I., Bebelis, S., Lyberatos, G., 2021. On the evaluation of filtered and pretreated cheese whey as an electron donor in a single chamber microbial fuel cell. Biomass Conversion and Biorefinery, 11(2): 633-643.
📄 Asunis, F., Sanna, A., Meli, V., Orsini, M., 2020. Valorization of cheese whey through biotechnological and chemical processes. Journal of Environmental Management, 275: 111231.
📄 Blais, J.F., Drouin, M., Mercier, G., 2022. Membrane technologies for dairy industry wastewater treatment and reuse. Separation and Purification Technology, 290: 120904.
📄 Carvalho, F., Prazeres, A.R., Rivas, J., 2013. Cheese whey wastewater: characterization and treatment. Science of the Total Environment, 446: 385–396.